Exosome therapy is one of the latest treatments of regenerative medicine. Regarded as the purest form of cell therapy, exosome therapy unlocks the healing potential within a person’s own cells, reducing chronic inflammation and supporting cellular and tissue regeneration. Exosome therapy involves administration into an affected joint or as an IV treatment.
What are exosomes?
Exosomes are small structures called micro-vesicles. About 1/1,000th the size of a cell, exosomes are important for cell-to-cell communication and regeneration.
The roles of exosomes, growth factors and cellular activity in regenerative medicine
Healing, repairing, reconstructing—this is the very nature of cells. Increased scientific understanding has revealed a revolutionary healing modality. This is true stem cell therapy—providing targeted treatment to the patient’s own cells by modulating the cellular activity.
This happens by introducing the patient’s cells to a healthy and younger combination of naturally occurring growth factor proteins and exosomes.
What are growth factors?
A growth factor is a naturally occurring protein capable of stimulating cellular growth, proliferation, healing, and cellular differentiation. Usually it is a protein or a steroid hormone. Growth factors are important for regulating a variety of cellular processes.
How are exosomes made?
Inside the cell, a cell membrane forms inward, forming a special type of lipid vesicle called an endosome. Then the proteins, microRNA and messenger RNA, invaginate the endosome’s membrane, forming the exosomes.
Endosomes then fuse with the surface of the cell, releasing the exosomes outside of the cell. Due to the observation of this process, historically, exosomes were believed to be a waste byproduct of cells. But when researched further, and it was discovered that, in fact, these are the mediating mechanisms involved in direct cell-to-cell communication.
Producing anti-inflammatory effects
These produce an anti-inflammatory response due to the communication from the many proteins that downregulate inflammatory proteins.
Other proteins will then recruit stem cells to the area that will help upregulate these cells to proliferate and promote organized healing through the regulated process. Then, once the task is complete, there are additional proteins that tell the cells when the healing has been completed.
These exosomes, with the presence of over 1,000-plus growth factors, are being regarded as one of the purest forms of stem cell therapy. In their natural state, they offer proteins and no DNA or potentially harmful byproducts that can be found in other therapies.
What are the potential benefits from exosome therapy?
Those with degenerative or autoimmune conditions could potentially benefit from exosome therapy as well as those wanting:
- To reduce pain and inflammation
- To speed up recovery from an injury
- To improve the body’s overall healing ability